Aleem Gangjee, Ph.D.
Scientific Director, AA/AT Program
Aleem Gangjee, Ph.D., serves as the scientific director for the Anti-angiogenic & Anti-tubulin (AA/AT) platform. A distinguished professor of medicinal chemistry at the Duquesne University School of Pharmacy, Dr. Gangjee is an internationally renowned scientist and author of dozens of U.S. and international patents. As a researcher, his broad expertise spans synthetic medicinal chemistry, computer-assisted drug design, antimitotic agents and antitumor agents.
Dr. Gangjee earned his B.S. in chemistry and M.S. in organic chemistry from the Indian Institute of Technology and his Ph.D. in medicinal chemistry from the University of Iowa. Among his many honors, Dr. Gangjee was named the recipient of the 2012 Research Achievement Award in Drug Discovery and Development Interface from the American Association of Pharmaceutical Scientists (AAPS).
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Larry Matherly, Ph.D.
Scientific Director, PSI program
Larry Matherly, Ph.D., serves as the scientific director for the Purine Synthesis Inhibitor (PSI) platform. He leads studies aimed toward drug discovery and translational studies of chemotherapy response and resistance. Dr. Matherly has been instrumental in the development of FLAG’s PSI platform and continues to push the first-in-class technology in new, innovative directions. His research has long focused on studies of transport processes for natural folates and folate analogs. These include the widely expressed reduced folate carrier (RFC), the proton-coupled folate transporter (PCFT) and the high affinity folate receptors (FRs).
In addition to his work with FLAG, Dr. Matherly serves as the associate center director for basic sciences at Karmanos Cancer Institute, the leader of the Molecular Therapeutics (MT) Program at Karmanos and as a professor in the Department of Oncology at Wayne State University School of Medicine.
Dr. Matherly earned his B.S. in biology from New Mexico State University and his Ph.D. in biochemistry from Pennsylvania State University. He was awarded the 2016 Eunice and Milt Ring Endowed Chair for Cancer Research.
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James Bauler, M.A.
Director, Corporate Development
James Bauler, director of corporate development, has 20 years’ career experience building multinational organizations. James has held roles, including in government affairs, business development and corporate development, in early-stage healthcare companies . James completed his master’s degree in international relations at the Tufts University Fletcher School of Law and Diplomacy and his B.A. in business investment finance at Wheaton College.
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Beth A. Slusar
Director, Program Management
Beth Slusar serves as the director of program management, having joined the company in 2014. Prior to her position at FLAG, Beth was the associate director of project management, responsible for the restructuring of the Project Management department, at Cirrus Pharmaceuticals. Beth has also worked at DPT Laboratories, Ltd. as a project manager, and was involved in pioneering the production of Taxanes from plant cell fermentation at Phyton Biotech. Beth’s 25 years in the pharmaceutical industry has spanned research and development, quality control and project management. She has a degree in chemistry from the State University of New York at Oswego.